While editing a document that already exists in iManage Work, select Save and Sync on the iManage tab to save your changes directly to iManage Work. The mouse pointer changes to the 'Saving...' notification to inform that iManage Work Desktop for Windows is saving the latest changes to iManage Work. The document remains open so that you can continue editing.
NOTE:
This overwrites the current version of the document. To save a new version, use Save as New Version.
If you select Save and Sync for a Microsoft Excel file without actually updating it, the modification date and file size gets changed and an entry for file modification is added to the Timeline.